Our research group investigates relationships between cognitive, socioemotional functions and endogenous sex steroids as well as synthetic substitutes of sex steroids (hormonal contraceptives). We focus on the evaluation of psychophysiological and behavioral parameters. We measure electrical brain activity (EEG, ERP), electrical activity of facial muscles (EMG), cardiovascular activity (ECG, HRV), and eye movements while participants perform tasks related to cognitive functions (mental rotation, verbal functions, etc.), emotions recognition and empathy, functional brain lateralization etc. Saliva serves as the source for determination of the sex steroids using ELISA method.



Methods and equipment:

• EEG recording - 64 channels ASA Lab system;
• EEG analysis – Matlab, EEGLab, Ragu, sLORETA;
• Other physiological measurements - PowerLab data acquisition hardware and LabChart software;
• Stimuli presentation - E-Prime software;
• Quantitative sex steroid hormones (estradiol, progesterone, testosterone) determination in saliva - ELISA assay.


Group members

ramune gri.1


Group leader

PhD, Assoc. Prof. Ramunė Grikšienė




PhD sudent

 Rimantė Gaižauskaitė



 ingrida zelionkaite1


PhD sudent

Ingrida Zelionkaitė





PhD sudent

Ieva Brimienė




PhD student

Erikas Ilkevič

lina galdutyte1 


MSc student

Lina Galdutytė 


milda brokeviciute1


MSc student

Milda Brokevičiūtė

 MSc students:

  • Kamilė Kupliauskaitė
  • Kostas Šimaitis
  • Roberta Morkūnaitė
  • Dominyka Kontrimaitė
  • Dominyka Brūzdaitė




 BSc student

Eglė Jašinskaitė

          Vilija Simonaitytė




Ongoing research. Invitation to participate



Rhythms in human body: the search for relationships between brain oscillations and fluctuations of sex hormones

“Rhythms in human body: the search for relationships between brain oscillations and fluctuations of sex hormones”, from the 1st june 2020 to the 15th december, 2020.

Main activities:

  1. June 2, 2023. Project start meeting, will be organized at Vilnius University, Life Sciences Center and online.
  2. June 2 - July 3, 2023. Final steps of the study, analysis of behavioral data, assessment of sex hormones in collected samples. Online training „EEG preprocessing and frequency analysis“.
  3. July 4 – 25, 2023 PhD and Master students visits at University of Münster to learn proposed EEG data analysis methods.
  4. September 20-22, 2023. Workshop “EEG analysis” will be organized at Vilnius University.


WorkshopEEG data analysis” 

20-22 September, 2023

Vilnius University, Life Sciences Center, Sauletekio ave. 7


20th September (Wednesday) Introductions. R402 auditorium

13-13.15 Opening. Coffee/Tea.

13.15 - 14 Lecture. Introduction to EEG. Ramunė Grikšienė, Vilnius University

14-16 Lecture. EEG oscillations. Elena Čėsnaitė, University of Munster

21st September (Thursday) Methods

R201 auditorium

10-11 Lecture. Preprocessing of EEG data. Elena Čėsnaitė, University of Munster

Coffee/Tea Break 

11.30 - 13.30 Practicals*:

  • Preprocessing of resting state EEG. Elena Čėsnaitė (University of Munster), Rimantė Gaižauskaitė, Ingrida Zelionkaitė, Vilnius University

  • Analysis of oscillations (periodic, aperiodic activity). Lina Gladutytė, Vilnius University Elena Čėsnaitė (University of Munster)

Lunch break

R404 auditorium

14.30 -16.00 Lecture and Practical. Automated preprocessing of EEG data. Valdas Noreika, Queen Mary University of London.

Coffee/Tea Break

16.15-18.00 Lecture and Practical. Multivariate source separation. Rasa Gulbinaitė, Netherlands Institute for Neuroscience, Amsterdam.

22nd September (Friday) Applications

R103 auditorium

10-11 Lecture. Mothers-babies EEG hyperscanning. Valdas Noreika, Queen Mary University of London

11-11.30 Lecture The search for relationships between EEG parameters and female hormonal satus. Ingrida Zelionkaite, Vilnius University.

11.30 - 13 Discussion. Coffee/Tea 

Participation in the Workshop is free, but the number of places is limited, and registration is required.

All participants will receive a certificate of attendance (17 hours).

* Note: if you want to follow the practical part and try the analysis steps together with us - please bring your own laptop!

This project of the Baltic-German University Liaison Office is supported by the German Academic Exchange Service (DAAD) with funds from the Foreign Office of the Federal Republic Germany.

hochschulkontor logo jpg

More information about the project: http://www.hochschulkontor.lv/en/projekti/atbalstitie-projekti/rhythms-in-human-body-the-search-for-relationships-between-brain-oscillations-and-fluctuations-of-sex-hormones/

Lateralization of cerebral hemispheres in foreign language and working memory processing


The processing of highly salient and biologically relevant emotional stimuli: gender differences and relationship to sex steroids

"The processing of highly salient and biologically relevant emotional stimuli: gender differences and relationship to sex steroids", from the 1st June 2023 to the 01th November, 2020

In collaboration with colleagues from Tübingen (Germany) and Tartu (Estonia) Universities our group is implementing a project which the main goal is knowledge sharing and collaboration in the area of emotion research and psychoneuroendocrinology between the project partners. Hence, emotion perception and regulation research will take place at the Vilnius University; we will organize project partners’ meetings, emotion research workshops and results presenatation in various conferences including one organized by the Lithuanian Neurocscience Association.

All partners will collaborate to design and conduct a reseach to evaluate how men and women recognize and regulate emotions. For this purpose both subjective and objective (brain imaging) methods will be used. Knowing that sex steroid balance has a signficant effect on emotions, women who use hormonal contraceptives will be one of the focus points.

Collaboration between partners will be maintained both through live meetings and remote work. First results and existing knowledge on the topic will be presented during two events in November 2020 – workshop “Emotion perception and regulation” and the 12th Conference of the Lithuanian Neuroscience Association. 


hochschulkontor logo transparent

More information about the project:  http://www.hochschulkontor.lv/en/projekti/atbalstitie-projekti/the-processing-of-highly-salient-and-biologically-relevant-emotional-stimuli-gender-differences-and-relationship-to-sex-steroids/


5th November, 11 am - 3 pm.

WEBINAR From emotion perception to regulation: workshop on socio-emotional functions.

WHERE. Online (link will be sent to registered e-mail) or in Life science center, Vilnius University, Sauletekio ave. 7, R102. More information abouth this event here.

REGISTRATION to Webinar and/or Public event: https://bit.ly/2GC9mkM



22 – 23 June 2020. Project start meeting, was organized in Vilnius University, Life Sciences Center and online.

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2021 Graduates- Livija Šarauskytė, Mykolas Gudaitis, Indrė Pretkelytė, Karolina Čižaitė, Karolina Jakštaitė.

mykolas ir livija1


indre pretkelyte1

 Indrė Pretkelytė

 karolina jakstaite1

       Karolina Jakštaitė

 karolina cizaite1

        Karolina Čižaitė


2020  Graduates - Aurelija Putramentaitė, Ričardas Baliutis, dr. Rasa Mončiunkaitė


aurelija            rasa1

2019  Graduates- Ernestas Švedas ir Rimantė Gaižauskaitė

 2019 m. absolventai

2017 m. Graduates: Dorita Bimbirytė, Ieva Lukštatitė, Julijus Motiejūnas, Benedikta Lataitytė

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Prof. Birgit Derntl, Tubingen University, Germany.

Dr. Helen Uusberg and Dr. Andero Uusberg, Tartu University, Estonia.

Prof. Markus Hausmann, Durham University, UK.

Thomas Koenig, Associate Proffesor at the Medical Faculty of the University of Bern



Brimienė I., Šiaudinytė M., Burokas A., Grikšienė R (2023) // Exploration of the Association between Menopausal Symptoms, Gastrointestinal Symptoms, and Perceived Stress: survey-based analysis. Menopause. Accepted. 2023-07-27.

R. Griksiene, R. Gaizauskaite, I. Pretkelytė, M. Hausmann (2022) // Lateral bias in visual working memory. // Symmetry, 14(12), 2509; https://doi.org/10.3390/sym14122509 . IF 2.94

B. Pletzer, C. Lang, B. Derntl, R. Griksiene (2022) // Weak associations between personality and contraceptive choice. // Frontiers in Neuroscience, section Neuroendocrine science. https://doi.org/10.3389/fnins.2022.898487. IF 5.15.

Griksiene, R. Monciunskaite, O. Ruksenas (2022) What is there to know about the effects of progestins on the human brain and cognition? (Review) // Frontiers in Neuroendocrinology, 67, 101032, https://doi.org/10.1016/j.yfrne.2022.101032 , IF 8.33

L. Sarauskyte, R. Monciunskaite, R. Griksiene (2022) The role of sex and emotion on emotion perception in artificial faces: an ERP study. // Brain and Cognition, 159, 105860. https://doi.org/10.1016/j.bandc.2022.105860.

R. Griksiene, A. Arnatkeviciute, R. Monciunskaite, T. Koenig, O. Ruksenas (2019) Mental rotation of sequentially presented 3D figures: sex and sex hormones related differences in behavioural and ERP measures. // Scientific Reports, 10.1038/s41598-019-55433-y, www.nature.com/articles/s41598-019-55433-y.

R. Monciunskaite, L. Malden, I. Lukstaite, O. Ruksenas, R. Griksiene (2019) Do oral contraceptives modulate an ERP response to affective pictures? // Biological Psychology, 148, 107767, doi.org/10.1016/j.biopsycho.2019.107767.

R. Griksiene, R. Monciunskaite, A. Arnatkeviciute, O. Ruksenas (2018) Does the use of hormonal contraceptives affect the mental rotation performance? // Hormones and behavior, 100, 29–38

I. Griskova-Bulanova, R. Griksiene, A. Voicikas, O. Ruksenas (2016) Go and NoGo:  modulation of electrophysiological correlates by female sex steroid hormones. // Psychopharmacology, 1-9. DOI 10.1007/s00213-016-4311-0.

D. Noreika, I. Griskova-Bulanova, A. Alaburda, M. Baranauskas, R. Griksiene (2014) Progesterone and mental rotation task: is there any effect? BioMed Research International, Volume 2014, Article ID 741758, 9 pages.

I. Griskova-Bulanova, R. Griksiene, M. Korostenskaja, O. Ruksenas (2014) 40Hz auditory steady-state response in females: when is it better to entrain? Acta Neurobiologiae Experimentalis, 74(1):91-7.

Zakevicius M., Liesiene V., Griksiene R., Masaitiene R., Ruksenas O. Arousals and Macrostructure of Sleep: Importance of NREM Stage 2 Reconsidered. Sleep Sci. 2013; 6 (3): 91-97.

R. Griksiene, O. Ruksenas (2011) Effects of hormonal contraceptives on mental rotation and verbal fluency. //Psychoneuroendocrinology, 36 (8), 1239-1248.

L. Maciukaitė, R. Griksiene, O. Ruksenas (2010) Estimation of affective pictures in different phases of menstrual cycle. // Psichologija (in Lithuanian), 41, 111-122

R. Griksiene, O. Ruksenas (2009) Cognitive effects of hormone based contraception in young healthy women. // Biologija, 55(3-4), 115-124.

R. Griksiene, O. Ruksenas (2003) Reaction of cardiovascular system to stressors during different phases of menstrual cycle. Laboratory medicine (in Lithuanian), 2 (18), 17-23.

Science popularization events

5th November, 5.30 pm - 7 pm.

PUBLIC EVENT „Why does my dog understand what I feel and you don't?“ This event will be held in Lithuanian and is open to everybody.

Pakalbėkime apie emocijas ir jausmus iš neuromokslų perspektyvos. Kas tai yra emocijos? Kur jos mumyse (smegenyse, širdyje, ..)? Kodėl mes (vyrai ir moterys) emocijas jaučiame, atpažįstame ir priimame skirtingai? Ar šie skirtumai blogai? O gal tai tiesiog daugiau spalvų mūsų kasdienybėje?

Sudomino? Kviečiame į atvirą paskaitą-diskusiją Kodėl mano šuo supranta ką jaučiu, o tu ne?"

Kada: Lapkričio 5 d. 17.30 – 19 val.

Kur: Vilniaus universiteto Gyvybės mokslų centre, Saulėtekio al. 7, R 102 a. ir Internete: https://bit.ly/30LS7V5

Daugiau informacijos čiaRegistracijos anketa čia



Ramune Griksiene

tel. +370 5 2398218

E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.